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Artifacts in Risk of Rain 2 rewrite the rules of a run. Some flip friendly fire on, others turn every spawn into an elite, and a few crank your damage to absurd numbers while leaving you with a sliver of health. Learn the codes, find the terminal, beat the boss, and your next run looks nothing like the last.
This guide covers where the terminal is, how the input grid works, what you need to fight the Reliquary, and every code with its effect.

The terminal lives in the Sky Meadow, which is always stage five of any run. Near the start of the level you will see a large pit in the floor. Drop into it. Hostile enemies sometimes block the descent, so either fight through them or sprint past.
At the bottom you'll find a 3x3 grid of nodes. Each cell cycles through floating shapes (circle, square, triangle, diamond) when you interact with it. Once the grid matches a valid code, walk to the laptop in front of the layout and use it. A portal opens at the teleporter behind you.
Step into the portal and you'll land in a hidden arena to face the Artifact Reliquary. The boss itself isn't really the puzzle. The trick is collecting four Artifact Keys, which drop from regular monsters spawning around the arena. Once you have all four, finish off the Reliquary and grab the artifact it leaves behind. That activates the effect for the rest of the run.
The list below covers all current artifact codes through the Devotion Update. Read each row top to bottom, three shapes per row, three rows total.
Once unlocked, multiple artifacts can run together. Stacking is where things get strange. Glass plus Swarms means flimsy allies trying to outpace twice as many enemies. Honor plus Kin guarantees every monster on the stage is an elite of the same type. Pick combos that match the run you want, not the run you barely survived last time.
That covers every code, the terminal location, and the Reliquary fight. Looking to run your own server for Risk of Rain 2? HolyHosting's Risk of Rain 2 server hosting is on the way.
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